It is well known that hands-on activities are an inseparable part of the nature of science. Experiments allow learners to understand and engage in a process of constructing knowledge by doing science. Ideally, students work with real equipment, and there’s no doubt that experiments in a real, wet laboratory are the best. But there may be some doubts. Nowadays, virtual science labs and online simulations have become an increasingly viable part of teaching and learning science. These media can provide unique active learning opportunities for students, visualization of scientific concepts, and development of basic scientific literacy.